- ￥118 - 2384
- TargetMol
- T4442
- 2026年07月07日
2 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- CAS号：
1314118-94-9
- 规格：
1mg/1mLx10mM(inDMSO)/5mg/10mg/25mg/50mg/100mg/200mg
| 规格： | 1mg | 产品价格： | ￥118.0 |
|---|---|---|---|
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥276.0 |
| 规格： | 5mg | 产品价格： | ￥248.0 |
| 规格： | 10mg | 产品价格： | ￥392.0 |
| 规格： | 25mg | 产品价格： | ￥729.0 |
| 规格： | 50mg | 产品价格： | ￥1160.0 |
| 规格： | 100mg | 产品价格： | ￥1640.0 |
| 规格： | 200mg | 产品价格： | ￥2384.0 |
Product Introduction
Bioactivity
| 名称 | MK2-IN-1 hydrochloride |
| 描述 | MK2-IN-1 hydrochloride (MK 25) is a highly selective, non-ATP competitive inhibitor of p38/mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2 or MK2, IC50: 0.11 μM) [1]. |
| 体外活性 | MK2-IN-1 has been shown to inhibit pro-inflammatory cytokine secretion from the human THP-1 acute monocytic leukemia cell line, causing inhibition of LPS-stimulated TNF-α (IC50: 4.4 μM) and IL-6 (IC50: 5.2 μM) secretion.1 It can also inhibit IL-1β-stimulated matrix-metalloprotease 13 secretion from the SW1353 chondrosarcoma cell line (IC50: 5.7 μM) and human primary chondrocyte cultures (IC50: 2.2 μM) [1]. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (1.96 mM), Sonication is recommended. DMSO : 50 mg/mL (98.15 mM), Sonication is recommended. H2O : Insoluble |
| 关键字 | MK2-IN-1 Hydrochloride | MK-2-IN-1 hydrochloride | MK2IN1 hydrochloride | MK-25 | MK25 | MK2 IN 1 hydrochloride | MK2 | Mitogen-activated protein kinase activated protein kinase 2 | MAPKAPK2 (MK2) | MAPKAP kinase 2 | MAPK activated protein kinase 2 | MAP kinase activated protein kinase 2 | Inhibitor | inhibit |
| 相关产品 | Mequinol | Sodium new houttuyfonate | Vemurafenib | 7-Aminocephalosporanic acid | Phosphocreatine disodium hydrate | Palmitic acid sodium | Tamoxifen Citrate | Palmitic acid | Benzbromarone | Ethoxyquin | Tamoxifen | Phosphocreatine disodium |
| 相关库 | Inhibitor Library | Bioactive Compound Library | Bioactive Compounds Library Max | Kinase Inhibitor Library | MAPK Inhibitor Library | HIF-1 Signaling Pathway Compound Library | Cytoskeletal Signaling Pathway Compound Library | Nonsteroidal Anti-Inflammatory Compound Library | Anti-Obesity Compound Library | Immunology/Inflammation Compound Library | Pain-Related Compound Library | Anti-Prostate Cancer Compound Library |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
官网有文献
相关实验
Acids Glycine 75 50 0.667 L-Alanine 89 25 0.281 L-Arginine 211 105 0.498 L-Asparagine-H2O 150 50 0.333 L-Aspartic acid 133 30 0.226 L-Cysteine hydrochloride-H2O 176 100 0.568 L-Cystine 2HCl 313 31 0.0990 L-
技术资料暂无技术资料 索取技术资料
文献支持
化合物 MK2-IN-1 hydrochloride【1314118-94-9】
￥118 - 2384
