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- CAS号：
55869-99-3
- 规格：
1mg/1mLx10mM(inDMSO)/5mg/10mg/25mg/50mg/100mg/500mg
| 规格： | 1mg | 产品价格： | ￥864.0 |
|---|---|---|---|
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥2776.0 |
| 规格： | 5mg | 产品价格： | ￥2528.0 |
| 规格： | 10mg | 产品价格： | ￥3624.0 |
| 规格： | 25mg | 产品价格： | ￥5496.0 |
| 规格： | 50mg | 产品价格： | ￥7560.0 |
| 规格： | 100mg | 产品价格： | ￥10160.0 |
| 规格： | 500mg | 产品价格： | ￥20400.0 |
Product Introduction
Bioactivity
| 名称 | Anisodamine |
| 描述 | Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation in states of shock and can be used in studies about organophosphate poisoning. |
| 体外活性 | 在RAW264.7细胞中，Anisodamine（100 μg/mL）阻断毒蕈碱受体，增加内源性ACh与α-7nAChR的结合，并减弱α-猪毒素的结合[3]。 |
| 体内活性 | 经腹腔给药，Anisodamine（50 mg/kg）显著降低了LPS诱导的休克小鼠的死亡率（20%）[3]。 |
| 存储条件 | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 150 mg/mL (491.21 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (10.81 mM), Sonication is recommended. 10% DMSO+90% Saline : 10 mg/mL (32.75 mM), Solution. H2O : 18 mg/mL (58.94 mM), Sonication is recommended. |
| 关键字 | Nicotinic Receptor | muscarinic receptor | Anisodamine | AChR | 6-β-Hydroxyhyoscyamine | 6-b-Hydroxyhyoscyamine |
| 相关产品 | Mitotane | Hexamethonium Bromide | Ethyl (triphenylphosphoranylidene) acetate | Urethane | Levamisole hydrochloride | Arecoline | Choline chloride | Adenine | N,N-Dicyclohexylcarbodiimide | Propoxur | Adiphenine hydrochloride | Ribavirin |
| 相关库 | Bioactive Compound Library | Bioactive Compounds Library Max | Selected Plant-Sourced Compound Library | Alkaloid Natural Product Library | Traditional Mongolian Medicine Compound Library | Anti-Alzheimer's Disease Compound Library | Traditional Chinese Medicine Monomer Library | Anti-Gastroenteritis Natural Product Library | Membrane Protein-targeted Compound Library | Anti-Neurodegenerative Disease Compound Library | Drug Repurposing Compound Library | Natural Product Library for HTS |
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山莨菪碱【55869-99-3】
￥864 - 20400
