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- 文献和实验
- 技术资料
- CAS号：
58546-54-6
- 规格：
1mLx10mM(inDMSO)/1mg/5mg/10mg/25mg/50mg/100mg/200mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥364.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥190.0 |
| 规格： | 5mg | 产品价格： | ￥396.0 |
| 规格： | 10mg | 产品价格： | ￥629.0 |
| 规格： | 25mg | 产品价格： | ￥1104.0 |
| 规格： | 50mg | 产品价格： | ￥1672.0 |
| 规格： | 100mg | 产品价格： | ￥2384.0 |
| 规格： | 200mg | 产品价格： | ￥3432.0 |
Product Introduction
Bioactivity
| 名称 | Schisandrol B |
| 描述 | 1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Schisandrol B significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation. |
| 存储条件 | Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (24.01 mM), Solution. DMSO : 245 mg/mL (588.29 mM), Sonication is recommended. 10% DMSO+90% Saline : < 10 mg/mL (24.01 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. |
| 关键字 | TJN101 | TJN 101 | Schisandrol B | ReactiveOxygenSpecies | Reactive Oxygen Species | P-glycoprotein | PCNA | p53 | p21 | lignan | Inhibitor | inhibit | Hepato-protective | Gomisin-A | Cytochrome P450 | CYPs | CYP3A11 | CYP2E1 | CCND1 | BCL-2 | Autophagy | antioxidant | anti-inflammatory | anti-diabetic |
| 相关产品 | Allopurinol | Kaolin | Guanidine hydrochloride | Naringin | Aceglutamide | Alginic acid | Hemin | Hydroxychloroquine | Stavudine | Ethoxyquin | Paeonol | Ethyl linoleate |
| 相关库 | Neuroprotective Compound Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Ancient Chinese Classical Formulas Compound Library | Anti-Tumor Natural Product Library | Anti-Aging Compound Library | Natural Product Library | Tobacco Monomer Library | Anti-Neurodegenerative Disease Compound Library | Immunology/Inflammation Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Anti-Cancer Drug Library |
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五味子醇乙【58546-54-6】
￥190 - 3432
