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穿琥宁【76958-99-1】

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  • ¥102 - 1976
  • TargetMol
  • T3667
  • 2026年07月07日
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    • CAS号

      76958-99-1

    • 规格

      1mLx10mM(inDMSO)/2mg/5mg/10mg/25mg/50mg/100mg/500mg

    规格:1mLx10mM(inDMSO)产品价格:¥215.0
    规格:2mg产品价格:¥102.0
    规格:5mg产品价格:¥158.0
    规格:10mg产品价格:¥213.0
    规格:25mg产品价格:¥372.0
    规格:50mg产品价格:¥542.0
    规格:100mg产品价格:¥789.0
    规格:500mg产品价格:¥1976.0

    Product Introduction

    Bioactivity

    名称 Kalii Dehydrographolidi Succinas
    描述 Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) is a natural compound with anti-virus infection activity.
    激酶实验 In vitro kinase assay is based on a filter binding assay, using the recombinant GST-fused kinase domains expressed in baculovirus and purified over glutathione-sepharose, γ-[33P]ATP as the phosphate donor, and poly(Glu:Tyr 4:1) peptide as the acceptor. Each GST-fused kinase is incubated under optimized buffer conditions [20 mM Tris-HCl buffer (pH 7.5), 1-3 mM MnCl2, 3-10 mM MgCl2, 3-8 μg/mL poly(Glu:Tyr 4:1), 0.25 mg/mL polyethylene glycol 20000, 8 μM ATP, 10 μM sodium vanadate, 1 mM DTT] and 0.2 μCi γ-33P ATP in a total volume of 30 μL in the presence or absence of a test substance for 10 min at ambient temperature. The reaction is stopped by adding 10 mL of 250 mM EDTA. Using a 384-well filter system, half the volume is transferred onto an Immobilon-polyvinylidene difluoride membrane. The membrane is then washed extensively and dried, and scintillation counting is performed. IC50s for compounds are calculated by linear regression analysis of the percentage inhibition[1].
    存储条件 Keep away from direct sunlight,Store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
    溶解度 10% DMSO+90% Saline : 0.94 mg/mL (1.65 mM), Solution.
    DMSO : 9.42 mg/mL (16.51 mM), Sonication is recommended.
    关键字 Potassium dehydroandrographolide | Kalii Dehydrographolidi Succinas | Inhibitor | inhibit
    相关产品 Penicillin G sodium salt | Penicillin G potassium | Ampicillin | Doxycycline | Neomycin sulfate | Terbinafine hydrochloride | Metronidazole | Ethyl acetoacetate | EDTA copper(II) disodium salt | Ampicillin sodium | Sulfamethoxazole sodium | Kanamycin sulfate
    相关库 Bioactive Compound Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Food as Medicine Compound Library | Anti-Aging Compound Library | Anti-Tumor Natural Product Library | Anti-Viral Compound Library | Natural Product Library | Anti-virus Traditional Chinese Medicine Monomer Library | Immunology/Inflammation Compound Library | Drug Repurposing Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS

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    文献支持
    穿琥宁【76958-99-1】
    ¥102 - 1976