- ￥5800 - 19200
- 上海经科
- 中国
- JK7930
- 2026年05月21日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 保质期：
3 months at -20°C
- 英文名：
IFN alpha/beta R1[Biotin], His & Avi, Human
- 库存：
现货
- 供应商：
上海经科化学科技有限公司
- 规格：
100μg/500μg
| 规格： | 100μg | 产品价格： | ￥5800.0 |
|---|---|---|---|
| 规格： | 500μg | 产品价格： | ￥19200.0 |
| Species | Human | ||||||
| Protein Construction |
|
||||||
| Conjugate | Biotin | ||||||
| Purity | > 95% as determined by BisTris PAGE | ||||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||||
| Expression System | HEK293 | ||||||
| Theoretical Molecular Weight | 50.2 kDa | ||||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 75-100 kDa based on Bis-Tris PAGE result. | ||||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
| Target Background | IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. |
| Synonyms | AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1 |
产品特点：
1. 【人源天然序列】采用人源 IFN alpha/beta R1 天然氨基酸序列，无突变，与体内天然蛋白结构完全一致，可特异性结合干扰素 α/β 配体2. 【高活性高特异性】可高效结合干扰素 α/β 配体，ED₅₀ < 100 ng/mL（配体结合实验），可被 IFN alpha/beta R1 特异性抗体识别，适用于抗体筛选、免疫机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%，内毒素 < 0.2 EU/μg（LAL 法），适配免疫细胞培养、体内免疫实验等敏感场景需求4. 【多标签易纯化检测】哺乳动物细胞表达，N 端带 Avi 标签、C 端带 His 标签，可通过 Ni-NTA 亲和层析快速纯化，也可通过 Avi/His 标签抗体、生物素亲和素系统进行特异性检测5. 【稳定易保存】蛋白储存液配方优化，未开封 - 80℃可稳定保存 12 个月，-20℃可存 6 个月，避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 IFN alpha/beta R1 蛋白结构与功能研究、免疫调控与炎症机制研究、肿瘤免疫治疗研究、细胞培养添加剂、药物筛选、抗体研发等
IFN alpha/beta R1, 干扰素 α/β 受体 1, 人源，人，重组蛋白，重组，高活性，高纯度，低内毒素，生物素标记，His 标签，Avi 标签，细胞培养，免疫细胞，科研实验，哺乳动物细胞表达Human,IFN alpha/beta R1,Interferon alpha/beta receptor 1,Recombinant protein,Biotin conjugated,His-tagged,Avi-tagged,High activity,High purity,Low endotoxin,Cell culture,Immune cell,Mammalian expression
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