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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 保质期:
3 months at -20°C
- 英文名:
IP-10/CXCL10, Human
- 库存:
现货
- 供应商:
上海经科化学科技有限公司
- 规格:
10μg/50μg/1mg
| 规格: | 10μg | 产品价格: | ¥400.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥1000.0 |
| 规格: | 1mg | 产品价格: | ¥7800.0 |
| Species | Human | |
| Protein Construction |
Expressed with an N-terminal Met.
|
|
| Purity | > 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC |
|
| Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | |
| Biological Activity | ED50 < 0.2 μg/ml, measured by a cell proliferation assay of HUVEC cells in the presence of 2.5 ng/ml h-VEGF, corresponding to a specific activity of > 5.0 × 103 U/mg. | |
| Expression System | E. coli | |
| Apparent Molecular Weight | ~8.6 kDa, on SDS-PAGE under reducing conditions. | |
| Formulation | Lyophilized after extensive dialysis against 50 mM Tris, pH 8.0. | |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml. | |
| Storage & Stability | Upon receiving, this product remains stable for 6 months at lower than -70°C. Upon reconstitution, the product should be stable for 1 week at 4°C or for 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
| Target Background | IP-10/CXCL10 also known as CXCL10, is originally identified as an IFN-γ-inducible gene in monocytes, fibroblasts and endothelial cells. It has since been shown that IP-10 mRNA is also induced by LPS, IL-1β, TNF-α, IL-12 and viruses. Additional cell types that have been shown to express IP-10 include activated T-lymphocytes, splenocytes, keratinocytes, osteoblasts, astrocytes, and smooth muscle cells. IP-10 is also expressed in psoriatic and lepromatous lesions of skin. The mouse homologue of human IP-10, Crg-2, has been cloned and shown to share approximately 67% amino acid sequence identity with human IP-10. |
| Synonyms | Small inducible cytokine B10; CXCL10; 10 kDa interferon-gamma-induced protein; Gamma-IP10; IP-10; chemokine (C-X-C motif) ligand 10; C7; IFI10; INP10; crg-2; mob-1; SCYB10; gIP-10 |
产品特点:
1. 【人源天然序列】采用人源 SPARC 天然氨基酸序列,无突变,与体内天然蛋白结构完全一致,可特异性结合细胞外基质成分2. 【高活性高特异性】可特异性结合 SPARC 抗体,ED₅₀ < 100 ng/mL(抗体结合实验),可被 SPARC 特异性抗体识别,适用于抗体筛选、细胞外基质机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%,内毒素 < 0.2 EU/μg(LAL 法),适配细胞培养、体内动物实验等敏感场景需求4. 【易纯化检测】哺乳动物细胞表达,可通过亲和层析快速纯化,也可通过 SPARC 特异性抗体进行检测5. 【稳定易保存】蛋白储存液配方优化,未开封 - 80℃可稳定保存 12 个月,-20℃可存 6 个月,避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 SPARC 蛋白结构与功能研究、细胞外基质与肿瘤侵袭机制研究、抗体制备与筛选、药物靶点验证、细胞培养添加剂等
SPARC, 富含半胱氨酸的酸性分泌蛋白,人源,人,重组蛋白,重组,高活性,高纯度,低内毒素,细胞培养,科研实验,哺乳动物细胞表达,Human,SPARC,Recombinant protein,High activity,High purity,Low endotoxin,Cell culture,Mammalian expression
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蛋白GP与NP是疫苗研发及免疫机制研究的核心靶点。 华美生物提供以下专业工具,助力病毒免疫学及治疗相关研究: ● 汉坦病毒检测试剂盒 ● 汉坦病毒重组蛋白 ➤细胞因子风暴相关靶点速通: TNF-a IL-6 L-7 IL-18 IL-33 CXCL10(IP-10) RANTES 3. 汉坦病毒传播途径 汉坦病毒主要传播途径为经鼠类动物传播,主要包括以下3种方式: 01.呼吸道传播 吸入携带病毒鼠类的尿液、粪便、唾液污染后形成的气溶胶; 02
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