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- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 保质期:
3 months at -20°C
- 英文名:
TECK/CCL25, Human
- 库存:
现货
- 供应商:
上海经科化学科技有限公司
- 规格:
20μg/1mg
| 规格: | 20μg | 产品价格: | ¥1200.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥18400.0 |
| Species | Human | |
| Protein Construction |
Expressed with an N-terminal Met.
|
|
| Purity | > 97% as analyzed by SDS-PAGE > 97% as analyzed by HPLC |
|
| Endotoxin Level | < 1 EU/μg of protein by LAL method | |
| Biological Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10.0 ng/ml. | |
| Expression System | E. coli | |
| Theoretical Molecular Weight | 14.3 kDa | |
| Formulation | Lyophilized from a 0.2 μm filtered solution in 20 mM PB, pH 7.4, 150 mM NaCl. | |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. | |
| Storage & Stability | Upon receiving, this product remains stable for 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for 1 week at 4°C or for 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
| Target Background | CCL25 (thymus expressed chemokine) is a novel CC chemokine that is distantly related (approximately 20% amino acid sequence identity) to other CC chemokines. Mouse CCL25 cDNA has also been cloned and shown to encode a 144 aa protein that exhibits 49% aa sequence identity to human CCL25. The expresssion of human and mouse CCL25 was shown to be highly restricted to the thymus and small intestine. Although dendritic cells have been demonstrated to be the source of CCL25 production in the thymus, dendritic cells derived from bone marrow do not express CCL25. |
| Synonyms | C-C motif chemokine 25; Small-inducible cytokine A25; Thymus-expressed chemokine; Chemokine TECK; CCL-25; SCYA25; TECK; Ckb15; MGC150327 |
产品特点:
1. 【人源天然序列】采用人源 TECK/CCL25 天然氨基酸序列,无突变,与体内天然蛋白结构完全一致,可特异性结合 CCR9 受体2. 【高活性高特异性】可高效趋化免疫细胞,ED₅₀ < 100 ng/mL(细胞趋化实验),可被 TECK 特异性抗体识别,适用于抗体筛选、免疫机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%,内毒素 < 0.2 EU/μg(LAL 法),适配免疫细胞培养、体内免疫实验等敏感场景需求4. 【易纯化检测】可通过亲和层析快速纯化,也可通过 TECK 特异性抗体进行检测5. 【稳定易保存】蛋白储存液配方优化,未开封 - 80℃可稳定保存 12 个月,-20℃可存 6 个月,避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 TECK 蛋白结构与功能研究、免疫调控与炎症机制研究、肿瘤免疫治疗研究、抗体制备与筛选、药物靶点验证、细胞培养添加剂等
TECK,CCL25, 胸腺表达趋化因子,人源,人,重组蛋白,重组,高活性,高纯度,低内毒素,免疫调节,细胞培养,免疫细胞,科研实验,哺乳动物细胞表达 Human,TECK,CCL25,Thymus-expressed chemokine,Recombinant protein,High activity,High purity,Low endotoxin,Immunomodulation,Cell culture,Immune cell,Mammalian expression
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