NF-κB p65 Mouse Monoclonal Antibody产品图

NF-κB p65 Mouse Monoclonal Ant

ibody
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  • ¥1350 - 2250
  • EnkiLife
  • AMM80783
  • 2026年07月23日
  • WB,IHC,ELISA
  • Mouse
  • Human,Mouse,Rat,Rabbit,Monkey
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 形态

      Liquid

    • 保存条件

      Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    • 标记物

      Unconjugated

    • 适应物种

      Human,Mouse,Rat,Rabbit,Monkey

    • 供应商

      武汉恩玑生命科技有限公司

    • 宿主

      Mouse

    • 应用范围

      WB,IHC,ELISA

    • 规格

      50uL/100uL

    规格:50uL产品价格:¥1350.0
    规格:100uL产品价格:¥2250.0

    产品概述

    产品名称(Product Name)

    NF-κB p65 Mouse Monoclonal Antibody

    描述(Description)

    Mouse monoclonal Antibody

    宿主(Host)

    Mouse

    应用(Application)

    WB,IHC,ELISA

    种属反应性(Reactivity)

    Human,Mouse,Rat,Rabbit,Monkey

     

    产品性能

    偶联物(Conjugation)

    Unconjugated

    修饰(Modification)

    Unmodified

    同种型(Isotype)

    Mouse IgG1

    克隆(Clonality)

    Monoclonal

    形式(Form)

    Liquid

    存放说明(Storage)

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    储存溶液(Buffer)

    Purified antibody in PBS with 0.05% sodium azide.

    纯化方式(Purification)

    Affinity Purification

     

    免疫原

    基因名(Gene Name)

    NF-κB p65

    别名(Alternative Names)

    NFkappaB p65; p65; NFKB3; RELA

    基因ID(Gene ID)

    5970

    蛋白ID(SwissProt ID)

    Q04206

     

    产品应用

    稀释比(Dilution Ratio)

    WB 1:500-1:2000,IHC 1:100-1:500,ELISA 1:5000-1:20000

    蛋白分子量(Molecular Weight)

    65kDa

     

    研究背景

    NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric RELA-NFKB1 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.

     

    研究领域

    PI3K-Akt signaling pathway,MAPK signaling pathway

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    图标文献和实验
    相关实验
    • Monoclonal Antibody Production

      and screening of the hybridomas: 1. Bleeding Mice (1) Place the mouse in a mouse restrainer. (2) Sterilize the tail with 70% ethanol. (3) With a razor blade,nip off the last 2 mm of the tip of the tail. (4) Using a milking motion,pull blood down and let

    • Rapid Isotyping of Mouse Monoclonal Antibodies

      Determination of class and subclass of monoclonal antibodies (MAbs) is important because several immunochemical and functional properties of antibodies depend on the isotype. Knowledge of the light-chain isotype (κ for 95% or λ

    • Monoclonal Antibody Production Protocol

      complete with MCM instead of PCM (= IMDM - m ), and keep it in the incubator for fused cells. Isolation of spleen cells Sacrifice mouse by cervical dislocation. Immerse mouse in 70% Ethanol. Remove spleen ( on the left side ) and transfer into a small

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