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CD276 Mouse Monoclonal Antibod

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  • ¥1350 - 2250
  • EnkiLife
  • AMM80893
  • 2026年04月17日
  • WB,IHC,ICC,ELISA,FC
  • Mouse
  • Human,Mouse,Rat,Rabbit,Monkey
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 形态

      Liquid

    • 保存条件

      Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    • 标记物

      Unconjugated

    • 适应物种

      Human,Mouse,Rat,Rabbit,Monkey

    • 供应商

      武汉恩玑生命科技有限公司

    • 宿主

      Mouse

    • 应用范围

      WB,IHC,ICC,ELISA,FC

    • 规格

      50uL/100uL

    规格:50uL产品价格:¥1350.0
    规格:100uL产品价格:¥2250.0

    产品概述

    产品名称(Product Name)

    CD276 Mouse Monoclonal Antibody

    描述(Description)

    Mouse monoclonal Antibody

    宿主(Host)

    Mouse

    应用(Application)

    WB,IHC,ICC,ELISA,FC

    种属反应性(Reactivity)

    Human,Mouse,Rat,Rabbit,Monkey

     

    产品性能

    偶联物(Conjugation)

    Unconjugated

    修饰(Modification)

    Unmodified

    同种型(Isotype)

    Mouse IgG1

    克隆(Clonality)

    Monoclonal

    形式(Form)

    Liquid

    存放说明(Storage)

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    储存溶液(Buffer)

    Purified antibody in PBS with 0.05% sodium azide.

    纯化方式(Purification)

    Affinity Purification

     

    免疫原

    基因名(Gene Name)

    CD276

    别名(Alternative Names)

    B7H3; B7-H3; 4Ig-B7-H3; CD276

    基因ID(Gene ID)

    80381

    蛋白ID(SwissProt ID)

    Q5ZPR3

     

    产品应用

    稀释比(Dilution Ratio)

    WB 1:500-1:2000,IHC 1:100-1:500,ICC 1:50-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400

    蛋白分子量(Molecular Weight)

    57kDa

     

    研究背景

    Costimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

     

    研究领域

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    图标文献和实验
    相关实验
    • Monoclonal Antibody Production

      and screening of the hybridomas: 1. Bleeding Mice (1) Place the mouse in a mouse restrainer. (2) Sterilize the tail with 70% ethanol. (3) With a razor blade,nip off the last 2 mm of the tip of the tail. (4) Using a milking motion,pull blood down and let

    • 单克隆抗体 monoclonal antibody

        指仅对一种抗原决定基的纯粹的抗体。这类抗体不可能通过将抗原 胞的 Hybridoma,在试管内制成了纯粹的单克隆抗体。用某种抗原使动物产生免疫感应,对应于抗原之不同部分可制成各种不同的抗体复合体。然而,因为一个产生抗体的细胞,只能产生一种抗体,所以骨髓肿瘤细胞与产生抗体细胞间的细胞杂种,可形成边产生抗体边增殖的 hybridoma,将每个杂种细胞进行克隆(无性繁殖系)培养,则一个克隆的细胞群只由单种类产生同一抗体的细胞所组成,这样得到的就是单克隆抗体。此抗体在测定

    • Monoclonal Antibody Production Protocol

      complete with MCM instead of PCM (= IMDM - m ), and keep it in the incubator for fused cells. Isolation of spleen cells Sacrifice mouse by cervical dislocation. Immerse mouse in 70% Ethanol. Remove spleen ( on the left side ) and transfer into a small

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