Mouse Monoclonal Antibody to CD276

Mouse Monoclonal Antibody to C

D276
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  • ¥1280 - 2180
  • Tanda
  • 中国
  • TD-30103
  • 2025年10月29日
  • FCM、ELISA、IHC
  • Mouse
  • Human
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    • 详细信息
    • 技术资料
    • 免疫原

      peptide

    • 亚型

      IgG1

    • 形态

      Liquid

    • 保存条件

      -20℃

    • 克隆性

      mAb

    • 适应物种

      Human

    • 保质期

      1年

    • 目录编号

      TD-30103

    • 级别

      科研级

    • 库存

      88

    • 供应商

      武汉天德

    • 宿主

      Mouse

    • 应用范围

      FCM、ELISA、IHC

    • 靶点

      详询

    • 抗体英文名

      Mouse Monoclonal Antibody to CD276

    • 抗体名

      CD276

    • 规格

      100ul/50ul

    规格:100ul产品价格:¥2180.0
    规格:50ul产品价格:¥1280.0

    Mouse Monoclonal Antibody to CD276

     

    Description

    Costimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

    Specification

    Aliases B7H3; B7-H3; 4Ig-B7-H3; CD276
    Entrez GeneID 80381
    Swissprot Q5ZPR3
    clone 6A1
    WB Predicted band size 57kDa
    Host/Isotype Mouse IgG1
    Antibody Type Primary antibody
    Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
    Species Reactivity Human
    Immunogen Purified recombinant fragment of human CD276 expressed in E. Coli.
    Formulation Ascitic fluid containing 0.03% sodium azide.

    Application

    IHC 1/200 - 1/1000
    FCM 1/200 - 1/400
    ELISA 1/10000
       

    Product Image

    • Mouse Monoclonal Antibody to C
      Flow cytometric analysis of PC-3 cells using CD276 mouse mAb (green) and negative control (purple).
    • Mouse Monoclonal Antibody to C
      Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues (left) and ovarian cancer tissues (right) using CD276 mouse mAb with DAB staining.
     

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