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- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 保质期:
12 months
- 英文名:
Research Grade Anti-Human CD366/HAVCR2/TIM-3 (TQB2618)
- 供应商:
武汉益普生物科技有限公司
- 规格:
100μg/1mg
| 规格: | 100μg | 产品价格: | ¥2288.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥6788.0 |
| 产品名称 | Research Grade Anti-Human CD366/HAVCR2/TIM-3 (TQB2618) |
| 货号 | HV029066 |
| 描述 | Anti-Human CD366/HAVCR2/TIM-3 (TQB2618) ( HV029066 ) is a research-grade recombinant antibody targeting CD366 . Produced in mammalian cells with native-like glycosylation. Highlights Research Grade — For PK/PD studies, assay development, and ADA research. Native Glycosylation — Mammalian expression ensures native-like patterns. |
| 反应种属 | Human |
| 应用实验 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主/表达体系 | Human |
| 靶点 | T-cell immunoglobulin mucin receptor 3, HAVcr-2, TIMD-3, T-cell membrane protein 3, HAVCR2, Hepatitis A virus cellular receptor 2, CD366, TIMD3, TIM-3, TIM3, T-cell immunoglobulin and mucin domain-containing protein 3 |
| 基因号 | Q8TDQ0 |
| 状态 | Liquid |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 储存温度 | -20℃ |
| 别名 | TQB2618 |

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文献和实验-bin/carddisp.pl?gene=HAVCR2&keywords=CD366 TIM3作为重要的细胞免疫负调控因子,高表达于辅助型T细胞(Thl细胞)和细胞毒性T细胞中(Tcl细胞),并产生抑制信号从而导致Thl细胞和Tcl细胞的凋亡。其配体为半乳凝素9(Gal-9),这是一种被广泛表达的可溶性分子[7],与TIM3分子的免疫球蛋白可变区上的寡聚糖结合,从而对Thl驱动的免疫反应产生负调控作用。当TIM3与其配体半乳凝素9(Gal-9)结合后,促进Thl细胞凋亡[8] 。也就是说
) A431 cells. At 48 h after infection, these cells were stained with ten different primary antibodies (5 g/ml) specific for different cell surface markers: anti-CD15 (clone 2F3; BD, PharMingen, San Diego, CA), anti-ERBB-2 (clone SP77; ref. 5), anti-ERBB
-ChIP and X-ChIP. - http://www.abcam.com/index.html?pageconfig=resource&rid=10418&CFID=2422773&CFTOKEN=36329956 Expert protocols and tips for N-ChIP and X-ChIP. AbCAM Immunoprecipitation of Chromatin from Fixed Yeast Protocol PDF - http
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