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Bedinvetmab

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  • ¥598 - 2488
  • abinScience
  • France
  • CF909016
  • 2026年04月12日
  • ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Caninized
  • Dog
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    • 详细信息
    • 技术资料
    • 亚型

      IgG2, lambda

    • 形态

      Liquid

    • 保存条件

      -20°C

    • 克隆性

      单克隆

    • 适应物种

      Dog

    • 保质期

      12 months

    • 级别

      一抗

    • 供应商

      武汉益普生物科技有限公司

    • 宿主

      Caninized

    • 应用范围

      ELISA, Bioactivity: FACS, Functional assay, Research in vivo

    • 抗体英文名

      Research Grade Bedinvetmab

    • 规格

      100μg/1mg

    规格:100μg产品价格:¥598.0
    规格:1mg产品价格:¥2488.0
    产品名 Research Grade Bedinvetmab
    货号 CF909016
    别名 ZTS-00508841, 2171034-69-6
    表达系统 Mammalian Cells
    靶标 NGF/Beta-NGF
    Accession号 F1PDQ3
    宿主 Caninized
    种属反应性 Dog
    克隆性 Monoclonal
    同种型 IgG2, lambda
    内毒素水平 Please contact the lab for this information.
    纯度 >95% purity as determined by SDS-PAGE.
    应用 ELISA, Bioactivity: FACS, Functional assay, Research in vivo
    纯化方式 Protein A/G purified from cell culture supernatant.
    状态 Liquid
    背景 Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs.
    • Encapsulation of β-NGF in injectable microrods for localized delivery accelerates endochondral fracture repair., PMID:37284244
    • New insights of the role of β-NGF in the ovulation mechanism of induced ovulating species., PMID:30763273
    • Effect of the Camelid's Seminal Plasma Ovulation-Inducing Factor/β-NGF: A Kisspeptin Target Hypothesis., PMID:28713816
    • β-NGF and β-NGF receptor upregulation in blood and synovial fluid in osteoarthritis., PMID:28253191
    • The β-NGF/TrkA Signalling Pathway Is Associated With the Production of Anti-Nucleoprotein IgG in Convalescent COVID-19., PMID:35095908
    • HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy., PMID:38646645
    • Heterologous beta-nerve growth factor (β-NGF) given at the LH surge enhances luteal function in dairy heifers., PMID:34186420
    • β-NGF Stimulates Steroidogenic Enzyme and VEGFA Gene Expression, and Progesterone Secretion via ERK 1/2 Pathway in Primary Culture of Llama Granulosa Cells., PMID:33195615
    • Ovulation mechanism in South American Camelids: The active role of β-NGF as the chemical signal eliciting ovulation in llamas and alpacas., PMID:32088046
    • Astragaloside‑IV modulates NGF‑induced osteoblast differentiation via the GSK3β/β‑catenin signalling pathway., PMID:33179111
    保存溶液 0.01M PBS, pH 7.4.
    稳定性和存储 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
     说明 For research use only. Not suitable for clinical or therapeutic use.

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    Bedinvetmab
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