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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
武汉研升生物科技有限公司
- 检测范围:
0.39ng/mL
- 检测方法:
Sandwich
- 适应物种:
Homo sapiens (Human)
- 样本:
serum, plasma, tissue homogenates
- 灵敏度:
Immunology
- 规格:
96T/48T
| 规格: | 96T | 产品价格: | ¥3600.0 |
|---|---|---|---|
| 规格: | 48T | 产品价格: | ¥2500.0 |
| Product Name |
Human Low affinity immunoglobulin gamma Fc region receptor III-B(FCGR3B) ELISA Kit |
| Chinese Name |
人低亲和力免疫球蛋白γFc区受体III-B(FCGR3B)ELISA Kit |
| Code |
CSB-EL008544HU |
| Alternative Names |
CD16 ELISA Kit; CD16b ELISA Kit; CD16b antigen ELISA Kit; Fc fragment of IgG low affinity IIIb receptor ELISA Kit; Fc gamma receptor IIIb ELISA Kit; Fc gamma RIII ELISA Kit; Fc gamma RIII beta ELISA Kit; Fc gamma RIIIb ELISA Kit; Fc-gamma RIII ELISA Kit; Fc-gamma RIII-beta ELISA Kit; Fc-gamma RIIIb ELISA Kit; FCG3 ELISA Kit; FCG3B_HUMAN ELISA Kit; FCGR3 ELISA Kit; FCGR3B ELISA Kit; FcR 10 ELISA Kit; FcR-10 ELISA Kit; FcR10 ELISA Kit; FcRIII ELISA Kit; FcRIIIb ELISA Kit; IGFR3 ELISA Kit; IgG Fc receptor III 1 ELISA Kit; IgG Fc receptor III-1 ELISA Kit; Low affinity immunoglobulin gamma Fc region receptor III B ELISA Kit; Low affinity immunoglobulin gamma Fc region receptor III-B ELISA Kit |
| Target Name |
Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| Abbreviation |
FCGR3B |
| Uniprot No. |
O75015 |
| Species |
Homo sapiens (Human) |
| Sample Types |
serum, plasma, tissue homogenates |
| Detection Range |
1.56ng/mL-100ng/mL |
| Sensitivity |
0.39ng/mL |
| Assay Principle |
quantitative |
| Measurement |
Sandwich |
| Assay Time |
1-5h |
| Sample Volume |
50-100ul |
| Detection Wavelength |
450nm |
| Research Area |
Immunology |
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文献和实验1 - - (小鼠) TCRγ/δ限制成分? 免疫球蛋白Fc段受体 polyIgR 100 - 1 4 1q31-q42 多聚Ig受体(肝细胞上 polyIgR是HBV受体) FcγRⅠ(CD64) 70 - 3 - 1q23-q24 IgG Fc高亲和力受体 FcγRⅡ(CD32) 40 - 2 - 1q23-q24 IgG Fc低亲和力受体 FcγRⅢ(CD16) 50~70 - 2 - 1q23-q24 IgG Fc低亲和力受体 FcεRⅠα链 25
Fc Engineering: Serum Half-Life Modulation Through FcRn Binding
Controlling the half-life of pharmaceuticals through Fc engineering is a desirable approach to achieve optimal exposure and targeting. The long serum residence time of gamma immunoglobulins is attributed to the Fc binding to the neonatal Fc
,合成由细胞脂质来源的介质如白三烯、前列腺素、血小板活化因子等,引起Ⅰ型变态反应。 2.调理吞噬作用 调理作用(opsonization)是指抗体、补体C3b、C4b等调理素(opsonin)促进吞噬细菌等颗粒性抗原。由于补体对热不稳定,因此又称为热不稳定调理素(heat-labile opsonin)。抗体又称热稳定调理素(heat-stable opsonin)。补体与抗体同时发挥调理吞噬作用,称为联合调理作用。中性粒细胞、单核细胞和巨噬细胞具有高亲和力或低亲和力的Fc&gamma
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