Purified recombinant protein o
f Human von Hippel-Lindau tumor suppressor-like (VHLL), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug- ￥2040
- OriGene
- TP760447
- 2026年03月19日
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- 文献和实验
- 技术资料
- 保存条件：
Store at -80°C.
- 保质期：
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
- 英文名：
Purified recombinant protein of Human von Hippel-Lindau tumor suppressor-like (VHLL), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
- 供应商：
OriGene
- 规格：
50 ug
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文献和实验Microarray Approaches for Analysis of Tumor Suppressor Gene Function
TP53 Tumor protein p53 WT1 Wilm’s tumor 1 VHL Von Hippel-Lindau syndrome
Polymerase Chain Reaction Detection of DNA Sequence Deletions
to disable tumor suppression (1 ). As might be expected, the effect of “two hits” on tumor-suppressor gene integrity—e.g., deletion of one allele and mutation of the remaining allele—would disable the gene from encoding gene product. The von Hippel-Lindau
, axin, and the tumor suppressor, adenomatouspolyposis coli (APC) protein (3) . In the absence of Wnt signaling,GSK-3 targets b-catenin for ubiquitin-mediated proteosomaldegradation by phosphorylation of b-catenin, axin, and APC (3) . Phosphorylation
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