Desk Clock/Calculator

拯救皱纹 + 脱发！张亮 / 李青峰 / 刘蔡钺团队解码抵抗

A stress-induced miR-31–CLOCK–ERK pathway is a key driver and therapeutic target for skin aging 的研究成果。该研究借助小鼠模型与临床样本数据，确定了一个关键的 miRNA 调节因子，并揭示了一个治疗相关的新途径：miR-31-CLOCK-ERK 偶联的信号通路是驱动皮肤上皮组织衰老的关键分子机制，这为将此通路作为临床干预靶点奠定了坚实的分子基础。图片来源：Nature Aging主要研究内容miR-31

三句话读懂一篇 CNS：补硒提高免疫力又添新证据；张锋开发新

., Yin, K., Zhang, X. et al. Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis. Nat Cancer (2021). https://doi.org/10.1038/s43018-021-00238-02. Yu, Y., Zhang, X., Liu, F. et al. A stress-induced miR-31–CLOCK–ERK pathway

Intracytoplasmic Spermatocyte Injection (ICSI)

easily in any direction (x y z) by means of a joystick. By simply pressing the joystick button, the capillary can repeatedly assume one of the pre-programmed positions. Sensibly, a point in the focal plane is chosen for the holding