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文献和实验CFTR Three-Dimensional Structure
CFTR is a member of the ATP-binding cassette family of membrane proteins. This is one of the best characterised membrane protein families in terms of structure and function. CFTR operates as an ion channel, unlike nearly all other family
Quantification of CFTR Transcripts
Quantification and analysis of CFTR transcripts is of crucial importance not only for cystic fibrosis (CF) diagnosis and prognosis, but also in evaluating the efficiency of various therapeutic approaches to CF, including gene therapy. Reverse
was named the cystic fibrosis transmembrane conductance regulator (CFTR) (11 ). Subsequently, CFTR has been reported to affect the activity of a large number of other ion channels and solute transporters (12 ). The chief interest in CFTR’ s ability
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