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- 50915-M08H
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- 详细信息
- 技术资料
- 保存条件：
50915-M08H
- 库存：
2
- 英文名：
Human Kallikrein-1, His (rHuKLK-1, His)
- 供应商：
50915-M08H
- 规格：
50ug
Kallikrein 1 Protein, Mouse, Recombinant (His Tag)
Cat: 50915-M08H
Cat: 50915-M08H
纯度
> 90 % as determined by SDS-PAGE
内毒素
< 1.0 EU per μg of the protein as determined by the LAL method
生物活性
Measured by its ability to cleave a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin(PFR-AMC).
The specific activity is >6, 000 pmol/min/μg.
(Activation description: The proenzyme needs to be activated by Thermolysin for an activated form)
The specific activity is >6, 000 pmol/min/μg.
(Activation description: The proenzyme needs to be activated by Thermolysin for an activated form)
蛋白构建
A DNA sequence encoding the mouse KLK1 (P15947) (Met1-Asp261) was expressed with a C-terminal polyhistidine tag.
Uniprot No.
表达宿主
HEK293 Cells
种属
Mouse
预测 N 端
Pro 19
分子量
The recombinant mouse KLK1 comprises 254 amino acids and has a predicted molecular mass of 28.3 kDa. The apparent molecular mass of the protein is approximately 36 kDa in SDS-PAGE under reducing conditions.
缓冲液
Lyophilized from sterile 25 mM Tris, 5 mM CaCl2, 0.15 M NaCl, pH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please contact us for any concerns or special requirements.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hardcopy of datasheet.
KLK1 (Kallikrein 1) is a Protein Coding gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. Human tissue kallikrein (KLK1) is a serine protease, a component of the KKS that has been demonstrated to exert pleiotropic beneficial effects in protection from tissue injury through its anti-inflammatory, antiapoptotic, antifibrotic, and antioxidative actions. Polymorphism of the human tissue kallikrein 1 (KLK1) A1789G gene is associated with susceptibility to hypertension. Diseases associated with KLK1 include Kallikrein, Decreased Urinary Activity Of and Hereditary Angioedema.
全称
kallikrein 1
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Kallikrein 1 Protein, Mouse, Recombinant (His Tag)
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