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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Mouse Ferritin heavy chain (Fth1)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Mouse Ferritin heavy chain (Fth1)品名简称:
Recombinant Mouse Fth1 protein货号:
CSB-EP009030MO规格:
20μg价格:
1536LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 95% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
Fth1Uniprot No.:
P09528别名:
Ferritin H subunit种属:
Mus musculus (Mouse)蛋白长度:
Full Length来源:
E.coli分子量:
28 kDa表达区域:
1-182aa氨基酸序列:
MTTASPSQVRQNYHQDAEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMECALHLEKSVNQSLLELHKLATDKNDPHLCDFIETYYLSEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDKHTLGHGDES蛋白标签:
C-terminal 6xHis-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
13-23 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.功能2:
/文献:
/研究领域:
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免疫疗法大升级!迟洪波课题组发现延长 T 细胞存活的关键蛋白
,与此同时还发现了 PTPN2 和 SOCS1 两个具有协同作用的靶点。该研究有望极大程度地提高相关肿瘤免疫疗法的治疗效果。图片来源: Nature研究内容图片来源: Nature由于此前的研究报道细胞代谢与癌症免疫治疗中的 T 细胞寿命关系密切,研究人员使用 CRISPR–Cas9 诱变筛选技术靶向了 OT-I Τ 细胞中 3017 个代谢相关的基因,在过继到患癌小鼠后,从小鼠的 B16 黑色素瘤中得到肿瘤浸润性淋巴细胞(tumour-infiltrating lymphocytes,TIL
和IgE。免疫球蛋白最显著的特点是与抗原特异性结合以及其分子的不均一性。 各种不同类别的免疫球蛋白分子都含有四条多肽链组成的基本结构单位,即由两条重链(heavy chain, H链)和两条轻链(light chain, L链)通过不同数目的二硫键结成Y形。在抗体分子的N端,不同抗体分子的氨基酸组成和顺序都是不同的,此区为“多变区”(variable region, V区),它是抗体分子与抗原决定簇的结合部位。由于抗体多变区这一结构特点,决定了它对抗原分子“识别功能”的多样性;不同抗体分子的C端
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