产品封面图
文献支持

CD66c/e (CEACAM 5/6) Antibody,

anti-human, PE, REAfinity™, 30 tests in 60 µL
收藏
  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-139-048
  • 2025年12月09日
  • Flow cytometry
  • human cell line
  • human
avatar
品牌商
14钻石会员
  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      CD66c/e (CEACAM 5/6)

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,4-8℃

    • 克隆性

      REA1395

    • 标记物

      PE

    • 适应物种

      human

    • 保质期

      24个月

    • 供应商

      Miltenyi biotec

    • 宿主

      human cell line

    • 应用范围

      Flow cytometry

    • 浓度

      1:50

    • 抗体英文名

      CD66c/e (CEACAM 5/6) Antibody, anti-human, REAfinity™

    • 抗体名

      CD66c/e (CEACAM 5/6) Antibody, anti-human, REAfinity™

    • 规格

      30 tests in 60 µL

    Identification and enumeration of CD66c/e (CEACAM 5/6)+ cells by flow cytometryClone REA1395 recognizes the human CD66c/e antigen. CD66c is a glycosylphosphatidylinositol (GPI) linked protein which is also known as Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) or NCA. Within the hematopoietic system, CD66c expression is limited to granulocytes and its precursors, where it serves homotypic and heterotypic adhesion, Ca2+ mediated signaling and is markedly upregulated from intracellular stores after activation. It is also found in epithelia of various organs. CD66c overexpression is found in a wide variety of epithelial cancer types such as lung, breast, colorectal, and hepatocellular carcinomas. CD66e antigen is a member of the Immunoglobin superfamily which is also known as CEA (carcinoembryonic antigen) or CEACAM5. CD66e is GPI-linked glycosylated protein found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. CD66e and other CEACAMs (CEA-related cell adhesion molecules) are host receptors for the Dr family of adhesins of Escherichia coli. CD66e is an intercellular adhesion molecule and is able to inhibit cellular differentiation. The overexpression of CD66e is used as an indicator for tumor invasiveness. | Additional information: Clone REA1395 displays negligible binding to Fc receptors. |

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献
    Neumaier, M. et al. (1988) Characterization of a cDNA clone for the nonspecific cross-reacting antigen (NCA) and a comparison of NCA and carcinoembryonic antigen. J. Biol. Chem. 263 (7): 3202–3207. | Taheri, M. et al. (2000) Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion. J. Biol. Chem. 275 (35): 26935–26943. | Korotkova, N. et al. (2008) Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation. Mol. Microbiol. 67 (2): 420–434. | Guillaume, N. et al. (2011) CD66c expression in B-cell acute lymphoblastic leukemia: strength and weakness. Int J Lab Hematol 33 (1): 92–96. | Kiyokawa, N. et al. (2014) Significance of CD66c expression in childhood acute lymphoblastic leukemia. Leuk. Res. 38 (1): 42–48.
    相关实验
    • Depression‐Related Behavioral Tests

      for incentive salience. Psychopharmacology 191:391‐431.    Binder, E., Malki, K., Paya‐Cano, J.L., Fernandes, C., Aitchison, K.J., Sluyter, F., and Schalkwyk, L.C. 2011. Antidepressants

    • Anti-HA Immunocytology

      To fix, 1/10 volume of 37 formaldehyde is added to the culture, which is shaken for a further 40 minutes at room temperature. Cells are then recovered by centrifugation at 1400 X g for 2 minutes, and washed (i.e. gently resuspended then recovered

    • Anti-HA Immunocytology

      of 0.75 to 1. To fix, 1/10 volume of 37% formaldehyde is added to the culture, which is shaken for a further 40 minutes at room temperature. Cells are then recovered by centrifugation at 1400 X g for 2 minutes, and washed (i.e. gently resuspended

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    询价
    德国美天旎生物技术有限公司
    2025年12月09日询价
    询价
    维百奥(北京)生物科技有限公司
    2025年07月06日询价
    询价
    上海沪震实业有限公司
    2025年07月15日询价
    询价
    上海信裕生物科技有限公司
    2025年07月09日询价
    ¥500
    北京百奥创新科技有限公司
    2025年07月09日询价
    文献支持
    CD66c/e (CEACAM 5/6) Antibody, anti-human, PE, REAfinity™, 30 tests in 60 µL
    询价