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- 详细信息
- 技术资料
- 免疫原:
CD86
- 亚型:
mouse IgG1
- 形态:
Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
- 保存条件:
避光,2-8℃
- 克隆性:
FM95
- 标记物:
pure
- 适应物种:
human, non-human primate
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Flow cytometry, Mass cytometry
- 靶点:
CD86
- 抗体英文名:
CD86 Antibody, anti-human
- 抗体名:
CD86 Antibody, anti-human
- 规格:
100 µg in 100 µL
Detection of CD86+ monocytes, monitoring of DC maturation by mass cytometryCD86, also known as B7-2 or B70, is an 80 kDa molecule and a member of the immunoglobulin superfamily. Together with CD80 (B7-1) it belongs to the B7 family of costimulatory molecules. CD86 is expressed on activated B and T cells, dendritic cells (DCs), and monocytes/macrophages. The interaction of CD86 with its ligands CD28 and CD152 (CTLA- 4) plays a critical role in induction and regulation of immune responses, e.g., cross-talk between T and B cells, T cell costimulation, or immunoglobulin class-switching. Binding of CD86 to CD28 on T cells results in transduction of costimulatory signals for activation or proliferation of T cells, or cytokine production.
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CD86 Antibody, anti-human, pure, 100 µg in 100 µL
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