- 询价
- Miltenyi Biotec
- 德国
- 130-126-439
- 2025年12月09日
- MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
S100A9
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL642
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名：
S100A9 Antibody, anti-human, REAdye_lease™
- 抗体名：
S100A9 Antibody, anti-human, REAdye_lease™
- 规格：
200 µL
Detection of S100A9+ cellsClone REAL642 is an antibody fragment derived from the full S100A9 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL642 recognizes the human S100A9 calcium- and zinc-binding protein, a S100 family member, which is also known as MRP14 (migration inhibitory factor-related protein 14) or calgranulin B. S100A9 is expressed in a wide range of cells but it is predominantly expressed in myeloid cells. S100A9 plays a crucial role in the regulation of inflammatory processes and immune response. S100A8 and S100A9 form the heterodimer calprotectin, that has proinflammatory, antimicrobial, apoptosis-inducing activities and different intracellular functions, for example facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the NADPH-oxidase. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
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文献和实验该产品被引用文献
Ryckman, C. et al. (2003) Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion. J Immunol 170 (6): 3233–3242. | Li, C. et al. (2009) A novel p53 target gene, S100A9, induces p53-dependent cellular apoptosis and mediates the p53 apoptosis pathway. Biochem. J. 422 (2): 363–372. | Rammes, A. et al. (1997) Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway. J. Biol. Chem. 272 (14): 9496–9502.
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S100A9 Antibody, anti-human, PE, REAdye_lease™, 200 µL
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