- 询价
- Miltenyi Biotec
- 德国
- 130-122-334
- 2025年12月09日
- Mass cytometry, Mass cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD86
- 亚型：
recombinant human IgG1
- 形态：
Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
- 保存条件：
避光，4-8℃
- 克隆性：
REA968
- 标记物：
pure
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
human cell line
- 应用范围：
Mass cytometry, Mass cytometry
- 抗体英文名：
CD86 Antibody, anti-human, REAfinity™
- 抗体名：
CD86 Antibody, anti-human, REAfinity™
- 规格：
100 µg in 100 µL
Identification and enumeration of CD86+ cells by mass cytometryClone REA968 recognizes the human CD86 antigen, also known as B7-2 or B70, which is an 80 kDa molecule and a member of the immunoglobulin superfamily. Together with CD80 (B7-1) it belongs to the B7 family of co-stimulatory molecules. CD86 is expressed on activated B and T cells, dendritic cells, and monocytes/macrophages. The interaction of CD86 with its ligands CD28 and CD152 (CTLA- 4) plays a critical role in induction and regulation of immune responses, e.g., cross-talk between T and B cells, T cell costimulation, or immunoglobulin class-switching. Binding of CD86 to CD28 on T cells results in transduction of costimulatory signals for activation or proliferation of T cells or cytokine production. | Additional information: Clone REA968 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Azuma, M. et al. (1993) B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366 (6450): 76–79. | Engel, P. et al. (1994) The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen. Blood 84 (5): 1402–1407. | Lanier, L. L. et al. (1995) CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. J Immunol 154 (1): 97–105.
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CD86 Antibody, anti-human, pure, REAfinity™, 100 µg in 100 µL
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