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- 详细信息
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture
- 英文名：
ORG 9426 Bromide
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
119302-91-9
- 规格：
10 mM * 1 mL/5 mg/10 mg/50 mg/100 mg/500 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥550.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥312.0 |
| 规格： | 10 mg | 产品价格： | ￥500.0 |
| 规格： | 50 mg | 产品价格： | ￥700.0 |
| 规格： | 100 mg | 产品价格： | ￥950.0 |
| 规格： | 500 mg | 产品价格： | ￥1700.0 |
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Rocuronium Bromide
CAS No. : 119302-91-9
MCE 国际站：Rocuronium Bromide
产品活性：Rocuronium Bromide (ORG 9426 Bromide) 是氨基甾体类非去极化的神经肌肉受体抑制剂或肌肉松弛剂。
研究领域：Others
作用靶点：Others
In Vitro: Rocuronium reduced the indirectly elicited twitch tensions in normal (50% inhibitory concentration [IC(50)], 9.84 [9.64-10.04] μM, mean [95% confidence interval]) and all pretreated diaphragms (P < .01, n = 6) in a concentration-dependent fashion [1]. The ED95 of rocuronium is essentially the same for children as for adults. Its duration of action is similar to vecuronium, and it is shorter for children than for adults. Rocuronium is readily reversed with conventional doses of cholinesterase-inhibiting drugs [2]. Onset time until maximum block, duration until 25% recovery of twitch height, and recovery from 25 until 75% of twitch height were 1.7 (32), 53 (19) and 20 (37) min, respectively [3].
In Vivo: Only 8.7±5.7% (SD) and 6.0±2.8% of an injected dose of ORG 9426 and ORG 9616 was excreted into the urine, respectively. Conversely, 54.4±9.2% and 52.4±9.2% of an injected dose of ORG 9426 and 35.7±12.2% and 46.8±9.7% of ORG 9616 were excreted into the bile in cats without and with renal pedicle ligation, respectively [4].
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