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ab1276-50ug,Anti-SMC1A (phosph

o S966) antibody
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  • ¥3481
  • Abcam
  • ab1276-50ug
  • 2025年11月01日
  • 仅用科研
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      Anti-SMC1A (phospho S966) antibody

    • 应用范围

      仅用科研

    • 保质期

      见瓶身

    • 库存

      99

    • 供应商

      嘉兴亦高

    • 保存条件

      -20°

    • 规格

      50ug

    SMC1A also known as structural maintenance of chromosomes 1A is an essential component of the cohesin complex. This complex regulates the cohesion of sister chromatids ensuring accurate chromosome segregation during cell division. With a molecular mass of around 143 kDa SMC1A is expressed ubiquitously with higher levels in proliferating cells. It is a member of the SMC protein family possessing distinct N-terminal and C-terminal domains connected by a flexible coiled-coil region./ Biological function summary/ SMC1A forms a complex with other proteins most notably SMC3 RAD21 and STAG2. This complex is necessary for maintaining chromatid cohesion during the cell cycle's S and G2 phases. Furthermore SMC1A influences DNA repair specifically homologous recombination by maintaining genome stability. Through its associations SMC1A contributes to regulation of gene expression further illustrating its multifunctional role in cellular processes./

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    图标文献和实验
    该产品被引用文献
    Science advances 7: | PubMed 33627431 2021 The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesis. out Applications Unspecified application Species Unspecified reactive species Fei Yi, Ying Zhang, Zhijun Wang, Zhuo Wang, Ziwei Li, Tingting Zhou, Hongde Xu, Jingwei Liu, Bo Jiang, Xiaoman Li, Liang Wang, Ning Bai, Qiqiang Guo, Yi Guan, Yanling Feng, Zhiyong Mao, Guangjian Fan, Shengping Zhang, Chuangui Wang, Longyue Cao, Brian P O'Rourke, Yang Wang, Yanmei Wu, Boquan Wu, Shilong You, Naijin Zhang, Junlin Guan, Xiaoyu Song, Yingxian Sun, Shi Wei, Liu Cao
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    文献支持
    ab1276-50ug,Anti-SMC1A (phospho S966) antibody
    ¥3481