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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Anti-hnRNP F+H antibody [1G11]
- 应用范围:
仅用科研
- 保质期:
见瓶身
- 库存:
99
- 供应商:
嘉兴亦高
- 保存条件:
-20°
- 规格:
100ul
Heterogeneous nuclear ribonucleoproteins F and H (hnRNP F+H) are RNA-binding proteins with functions in pre-mRNA processing. Alternate names for these proteins include HNRNPF and HNRNPH. These proteins have molecular masses of approximately 46-49 kDa for hnRNP F and 49-50 kDa for hnRNP H. hnRNP F+H appears widely expressed in various tissues with elevated levels in cells with high transcriptional activity. They possess RNA recognition motifs that directly interact with specific RNA sequences facilitating RNA splicing and stability.
Biological function summary
HnRNP F+H influences mRNA splicing by binding to its substrates and regulating splicing events. The proteins often participate in complexes with other RNA-binding proteins contributing to spliceosome function. They regulate alternative splicing events and affect gene expression important in diverse cellular processes. These activities enable hnRNP F+H to modulate the expression of key genes involved in cell growth differentiation and stress responses.
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文献和实验该产品被引用文献
Cancers 14: | PubMed 35267591
2022
Translational Regulation by hnRNP H/F Is Essential for the Proliferation and Survival of Glioblastoma.
out
Applications
Unspecified application
Species
Unspecified reactive species
Morgane Le Bras, Noah Gorelick, Sylvain Pautet, Betty Tyler, Stéphane Manenti, Nicolas Skuli, Stefania Millevoi, Anne Cammas
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文献支持
ab10689-100ul,Anti-hnRNP F+H antibody [1G11]
¥3569


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