- ￥880
- Bioss
- bs-7815P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7815P |
| 英文名称 | NEK8 Antibody Blocking Peptide |
| 中文名称 | 丝氨酸/苏氨酸蛋白激酶NEK8封闭多肽 |
| 英文别名 | JCK; NEK 8; NEK12A; NEK8; NEK8_HUMAN; Never in mitosis A-related kinase 8; NIMA-family kinase NEK8; NIMA-related kinase 12a; Nima-related protein kinase 12a; NimA-related protein kinase 8; Serine/threonine-protein kinase Nek8. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Other cell division antibodies Cell Biology > Cell Cycle > Kinases/Phosphatases Epigenetics and Nuclear Signaling > Cell cycle > Kinases/Phosphatases |
| 亚基 | Interacts with PKD2; may regulate PKD2 targeting to thecilium (By similarity). |
| 亚细胞定位 | Cytoplasm (By similarity). Cytoplasm,cytoskeleton. Cell projection, cilium (By similarity).Note=Predominantly cytoplasmic. Localizes to the proximal region ofthe primary cilium and is not observed in dividing cells. |
| 组织特异性 | Highest expression in thyroid, adrenal glandand skin. Low levels in spleen, colon and uterus. Overexpressed inbreast tumors, with highest expression in infiltrating ductalcarcinomas and moderate levels in mucinous adenocarcinoma. |
| 相似性 | Belongs to the protein kinase superfamily. NEK Ser/Thrprotein kinase family. NIMA subfamily. Contains 1 protein kinase domain. Contains 5 RCC1 repeats. |
| 功能 | Required for renal tubular integrity. May regulate localcytoskeletal structure in kidney tubule epithelial cells. Mayregulate ciliary biogenesis through targeting of proteins to thecilia (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Required for renal tubular integrity.Tissue specificity: Highest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma. |
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NEK8 Antibody Blocking Peptide(bs-7815P)-500ug
￥880
