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- Bioss
- bs-2328P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-2328P |
| 英文名称 | pre S1/S2 protein Antibody Blocking Peptide |
| 中文名称 | 人乙肝病毒pre S1蛋白/HBV pre S1 protein封闭多肽 |
| 英文别名 | Hepatitis B Virus Surface Antigen; Hepatitis B virus S1/S2 protein; Hepatitis B virus PreS1; Hepatitis B virus pre S1 protein; HBV pre S1 protein; HBSAG_HBVD2; HBSAG_HBVC5; Hepatitis B Virus Major surface antigen; Large envelope protein; Large surface protein; L glycoprotein; Major surface antigen; Large S protein; L-HBsAg; LHB. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Viral proteins > Hepatitis B Microbiology > Organism > Virus > DNA Virus > double stranded DNA Virus > Hepatitis B |
| 亚基 | Li-HBsAg interacts with capsid protein and with HDV Large delta antigen. Isoform M associates with host chaperone CANX through its pre-S2 N glycan. This association may be essential for M proper secretion. |
| 亚细胞定位 | Virion membrane. |
| 翻译后修饰 | Isoform M is N-terminaly acetylated at a ratio of 90%, and N-glycosylated at the pre-S2 region.
Myristoylated. |
| 相似性 | Belongs to the orthohepadnavirus major surface antigen family. |
| 功能 | The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assumes fusion between virion membrane and endosomal membrane (Probable). In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein.
The middle envelope protein plays an important role in the budding of the virion. It is involved in the induction of budding in a nucleocapsid independent way. In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HBV surface proteins [Hepatitis B virus]. Major surface antigen from hepadnavirus; pfam00695. |
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pre S1/S2 protein Antibody Blocking Peptide(bs-2328P)-500ug
￥880
