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- Bioss
- bs-12342P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-12342P |
| 英文名称 | L3MBTL3 Antibody Blocking Peptide |
| 中文名称 | L3MBTL3蛋白封闭多肽 |
| 英文别名 | Hl(3)mbt like protein; KIAA1798; l(3)mbt like 3 (Drosophila); l(3)mbt like 3; L(3)mbt like 3 protein; Lethal(3)malignant brain tumor like 3 protein; MBT1; LMBL3_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Remodeling > Polycomb Silencing Stem Cells > Hematopoietic Progenitors > Myeloid > Myeloid Progenitor |
| 亚基 | Interacts with RNF2 (By similarity). |
| 亚细胞定位 | Nuclear. |
| 相似性 | Contains 3 MBT repeats. Contains 1 SAM (sterile alpha motif) domain. |
| 功能 | Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Polycomb group (PcG) proteins are important for maintaining the transcriptionally repressed state of target genes and are thought to function via chromatin modification. PcG proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. PcG proteins are also required for normal maturation of myeloid progenitor cells. A putative PcG protein, L3MBTL3 (lethal(3)malignant brain tumor-like protein 3), also known as MBT-1 or KIAA1798, is a 780 amino acid protein containing three MBT repeats and one SAM (sterile alpha motif) domain. Localized to the nucleus, L3MBTL3 interacts with RING1B, another PcG protein that may be involved in the specification of anterior-posterior axis and cell proliferation in early development. L3MBTL3 exists as two isoforms produced by alternative splicing events. |
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L3MBTL3 Antibody Blocking Peptide(bs-12342P)-500ug
￥880
