- ￥880
- Bioss
- bs-14475P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-14475P |
| 英文名称 | FXYD5 Antibody Blocking Peptide |
| 中文名称 | 抗粘附素封闭多肽 |
| 英文别名 | Dysad; Dysadherin; FXYD 5; FXYD domain containing ion transport regulator 5; FXYD domain-containing ion transport regulator 5; Fxyd5; FXYD5_HUMAN; FXYD5RIC; HSPC 113; HSPC113; IWU 1; IWU1; KCT 1; KCT1; Keratinocytes associated transmembrane protein 1; OIT 2; OIT2; PRO 6241; PRO6241; RIC. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Membrane. |
| 翻译后修饰 | Glycosylated. |
| 相似性 | Belongs to the FXYD family. |
| 功能 | Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin. It also promotes metastasis, and has been linked to a variety of cancers. Alternative splicing results in multiple transcript variants. [RefSeq curation by Kathleen J. |
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FXYD5 | Dysadherin Ab Blocking Peptide(bs-14475P)-500ug
￥880
