- ￥880
- Bioss
- bs-15404P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-15404P |
| 英文名称 | HAGH Antibody Blocking Peptide |
| 中文名称 | 羟酰谷胱甘肽水解酶蛋白封闭多肽 |
| 英文别名 | GLO2; GLX II; Glyoxalase II; HAGH; HAGH1; Hydroxyacyl glutathione hydrolase; Hydroxyacylglutathione hydrolase, mitochondrial; GLO2_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Monomer. |
| 亚细胞定位 | Isoform 1: Mitochondrion matrix. Isoform 2: Cytoplasm. |
| 组织特异性 | Expressed in liver and kidney. |
| 相似性 | Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. |
| 功能 | Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The glyoxal pathway plays a role in the detoxification of glucose degradation products (GDP). Glyoxalase I and Gyloxalase II (also designated hydroxyacyl glutathione hydrolase or HAGH) are members of the Gyloxalase family. The Gyloxalase II enzyme is a thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form reduced glutathione and D-lactic acid. It exists only as a monomer and binds two zinc ions per subunit. Glyoxalase II contains 260 amino acids. It is detected in the mitochondria and cytosol of mammals. Both Glyoxalase I and Gyloxalase II are detected at a higher activity level in breast cancer tissues than with matched unaffected tissues. This suggests that glyoxalase inhibitor drugs may be effective in the treatment of cancer. |
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HAGH Antibody Blocking Peptide(bs-15404P)-500ug
￥880
