- ￥880
- Bioss
- bs-11199P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11199P |
| 英文名称 | DBX1 Antibody Blocking Peptide |
| 中文名称 | 脑发育同源蛋白1封闭多肽 |
| 英文别名 | dbx; Developing brain homeobox 1; Developing brain homeobox protein 1; DBX1_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nuclear |
| 相似性 | Belongs to the H2.0 homeobox family. Contains 1 homeobox DNA-binding domain. |
| 功能 | Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Dbx1 homeodomain transcription factor is expressed in progenitors at the boundary between the dorsal and ventral plates of the caudal neural tube, from which postmitotic cells migrate tangentially to their final destination. Dbx1 is implicated in patterning the central nervous system during embryogenesis. Cell fate allocation and cell diversity are determined at very early stages in progenitor cells at precise coordinates along the dorsoventral and anteroposterior axis. In the spinal cord, the spatially restricted expression of Dbx1 in progenitors is critical in establishing interneuron cell fates and helps coordinate diverse phenotypic features. In the telencephalon, Dbx1 is expressed in restricted progenitor domains at the borders of the developing pallium. |
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DBX1 Antibody Blocking Peptide(bs-11199P)-500ug
￥880
