- ￥880
- Bioss
- bs-0089P
- 2025年10月16日
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500ug
| 产品编号 | bs-0089P |
| 英文名称 | SCTR Antibody Blocking Peptide |
| 中文名称 | 分泌素受体封闭多肽 |
| 英文别名 | 6530402O03Rik, MGC102218, MGC93381, SCTR, SR; Secretin receptor; SCT-R; SCTR_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Growth Factors/Hormones > Hormones Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the G-protein coupled receptor 2 family. |
| 功能 | This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The receptor for secretin is a class 2 (or class B) G protein coupled receptor that signals through Gs to stimulate cAMP production. Along with its traditional role in the pancreas, studies in secretin-deficient mice have shown miscommunication between the CA3 Schaffer collateral and CA1 pyramidal neurons, causing a deficiency in synaptic transmission. This miscommunication of CA1 dendrites is found in Autism, Rett Syndrome, and most forms of mental retardation, suggesting secretin could be a potential target for treatment of these disorders. |
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SCTR Antibody Blocking Peptide(bs-0089P)-500ug
￥880
