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DYNLT3 Antibody Blocking Pepti

de(bs-14472P)-500ug
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  • bs-14472P
  • 2025年10月16日
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      500ug

    产品编号bs-14472P
    英文名称DYNLT3 Antibody Blocking Peptide
    中文名称动力蛋白轻链Tctex-3封闭多肽
    英文别名2310075M16Rik; AU042796; DYLT3_HUMAN; Dynein light chain Tctex-type 3; DYNLT3; Protein 91/23; RP23-256J17.2; RP3; T-complex-associated testis-expressed 1-like; Tcte1l; TCTEX1L.
    纯化方法HPLC
    研究领域

    Cancer > Cell cycle > Cell division

    Cell Biology > Cell Cycle > Cell Division > Other cell division antibodies

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Dynein

    亚细胞定位Nucleus. Cytoplasm; cytoskeleton. Chromosome; centromere; kinetochore. Colocalizes with BUB3 at kinetochores specifically during prometaphase.
    相似性Belongs to the dynein light chain Tctex-type family.
    功能Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.[provided by RefSeq, Mar 2010]

     

     

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