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- Bioss
- bsm-30017M-APC
- 2026年05月21日
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25T/50T/100T
| 规格： | 25T | 产品价格： | ￥680.0 |
|---|---|---|---|
| 规格： | 50T | 产品价格： | ￥1080.0 |
| 规格： | 100T | 产品价格： | ￥1680.0 |
| 产品编号 | bsm-30017M-APC |
| 英文名称 | human CD16 Mouse mAb, APC conjugated |
| 中文名称 | APC标记人CD16单克隆抗体 |
| 英文别名 | FCG3A_HUMAN; Low affinity immunoglobulin gamma Fc region receptor III-A; CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; CD_antigen: D16a; FCGR3A; CD16A; FCG3; FCGR3; IGFR3. |
| 产品应用 | Flow-Cyt=10ul/Test Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 亚型 | Mouse IgG1, k |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 27 kDa |
| 实际分子量 | 50-65kDa |
| 储存液 | 0.01M PBS (pH7.4), 0.5% BSA, 0.02% Proclin300. |
| 研究领域 | Immunology > Cell Type Markers > CD > NK Cells Stem Cells > Hematopoietic Progenitors > Hematopoietic Stem Cells > Human Lineage Negative Stem Cells > Hematopoietic Progenitors > Lymphoid > NK Cell Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Monocytic Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Neutrophil Lineage |
| 亚基 | Exists as a heterooligomeric receptor complex with Fc epsilon receptor I gamma subunit and / or the CD3 zeta subunit. Interacts with INPP5D/SHIP1. |
| 亚细胞定位 | Cell membrane. Secreted. Exists also as a soluble receptor. |
| 组织特异性 | Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts. |
| 翻译后修饰 | Glycosylated. Contains high mannose- and complex-type oligosaccharides. The soluble form is produced by a proteolytic cleavage. [MISCELLANEOUS] Encoded by one of two nearly indentical genes: FCGR3A (Shown here) and FCGR3B which are expressed in a tissue-specific manner. The Phe-203 in III-A determines the transmembrane domains whereas the 'Ser-203' in III-B determines the GPI-anchoring. |
| 相似性 | Contains 2 Ig-like C2-type (immunoglobulin-like) domains. |
| 功能 | Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
| 保存条件 | Store at 2-8℃. Protect from light. Avoid freezing. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {10ul/Test} |
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文献和实验细胞研究，提供专业流式配色设计与高品质检测试剂，助力精准表型鉴定与功能分析。 以下为推荐抗体组合，适用于免疫细胞检测，欢迎咨询，让您的流式实验更精准可靠。 流式抗体推荐 种属 细胞群 流式抗体搭配 货号 Human T/B/NK细胞群检测 CD45-PerCP PCP-30039 CD3-FITC FITC-30004 CD16-PE PE-30061 CD56-PE PE-30008 CD19-APC APC-30066 Human Th1/Th2 细胞群检测 CD
CD56-PE PE-30008 CD19-APC APC-30066 Human Th1/Th2 细胞群检测 CD3-PerCP-Cy5.5 PCP55-30004 CD4-FITC FITC-30005 IFN-γ-PE PE-30053 IL4-APC APC-30043 Mouse Th1/Th2 细胞群检测 CD3-PerCP-Cy5.5 PCP55-30002 CD4-FITC
45-PerCP PCP-30039 CD3-FITC FITC-30004 CD16-PE PE-30061 CD56-PE PE-30008 CD19-APC APC-30066 Human Th1/Th2 细胞群检测 CD3-PerCP-Cy5.5 PCP55-30004 CD4-FITC FITC-30005 IFN-γ-PE PE-30053 IL4-APC APC-30043
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