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Granzyme A Rabbit pAb, FITC co

njugated(bs-2578R-FITC)-100ul
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  • ¥2980
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  • bs-2578R-FITC
  • 2025年10月15日
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      100ul

    产品编号bs-2578R-FITC
    英文名称Granzyme A Rabbit pAb, FITC conjugated
    中文名称FITC标记的颗粒酶A抗体
    英文别名CTL tryptase; CTLA3; Cytolytic t cell and natural killer cell specific trypsin like serine protease; Cytotoxic T lymphocyte associated serine esterase 3; Cytotoxic T lymphocyte proteinase 1; Cytotoxic T-lymphocyte proteinase 1; Fragmentin 1; Fragmentin-1; GRAA_HUMAN; Granzyme 1 cytotoxic T lymphocyte associated serine esterase 3; Granzyme A(Cytotoxic T lymphocyte associated serine esterase 3; Hanukah factor serine protease); Granzyme A(granzyme 1, cytotoxic T lymphocyte associated serine esterase 3); Granzyme A; Granzyme A precursor; Granzyme-1; GZMA; H factor; Hanukah factor serine protease; Hanukkah factor; HF; HFSP; TSP1.
    产品应用IF=1:50-200

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human GZMA
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Homodimer; disulfide-linked. Interacts with APEX1.
    亚细胞定位Isoform alpha: Secreted. Cytoplasmic granule.
    相似性Belongs to the peptidase S1 family. Granzyme subfamily.
    Contains 1 peptidase S1 domain.
    功能This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Involved in apoptosis.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    背景资料Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {IF}{1:50-200}

     

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