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- 详细信息
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- 应用范围:
产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-14001R |
| 英文名称 | ERPINA6/Cortisol Binding Globulin Rabbit pAb |
| 中文名称 | 皮质醇结合球蛋白抗体 |
| 英文别名 | CBG; CBG_HUMAN; corticosteroid binding globulin; Corticosteroid-binding globulin; serine(or cysteine) proteinase inhibitor clade A(alpha 1 antiproteinase antitrypsin) member 6; serpin A6; serpin peptidase inhibitor clade A(alpha 1 antiproteinase antitrypsin) member 6; SERPINA6; transcortin. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Cow, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Cortisol Binding Globulin |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 43 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. |
| 翻译后修饰 | N-glycosylated; binds 5 oligosaccharide chains. Glycosylation in position Asn-260 is needed for steroid binding. |
| 相似性 | Belongs to the serpin family. |
| 功能 | Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |

HepG2(Human) Cell Lysate at 30 ug
Primary: Anti- Cortisol Binding Globulin (bs-14001R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kD
Observed band size: 73 kD

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文献和实验[IF={{ 4.4 }}] {Guojun Weng. et al. Ag triangle nanoplates assembled on PVC/SEBS membrane as flexible SERS substrates for skin cortisol sensing. SPECTROCHIM ACTA A. 2023 Dec;303:123154} {Other} {}
[IF={{ 4.3 }}] {Yuan Liang. et al. Withaferin A: A potential selective glucocorticoid receptor modulator with anti-inflammatory effect. FOOD CHEM TOXICOL. 2023 Jul;:113949} {WB} {Human}
ANTIBODY BINDING TO PROTEIN A AND PROTEIN G
., Finstad, J., Williams, Jr., R. C. 1970. Phylogenetic insight into evolution of mammalian Fc fragment of g G globulin using staphylococcal protein A. J. Immunol. 104:140-147. Kronvall, G. 1973. A surface component in group A, C, and G streptococci
rabbit serum albumin 兔血清白蛋白 R-Sc Reed-Sternberg's cell 瑞-司氏细胞 Z/R Reinheit Zahl 光密度比值 SAV small agranular vesicle 无颗粒小泡 SBA soybean agglutinin 大豆凝集素 SC secretory component 分泌成份 SCV small clear vesicle 清亮小泡 SDS sodium
empty 网状结构上行激动系统 Ascending reticular activating system 位置性眼震颤 Positional nystagmus 舞蹈病 Chorea X 性激素结合球蛋白 Sex hormone-binding globulin
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