IL12 Rabbit pAb, HRP conjugated(bs-1789R-HRP)-100ul

IL12 Rabbit pAb, HRP conjugate

d(bs-1789R-HRP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-1789R-HRP
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-1789R-HRP
    英文名称IL12 Rabbit pAb, HRP conjugated
    中文名称HRP标记的白介素12抗体
    英文别名IL12A_HUMAN; Interleukin-12 subunit alpha; IL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit(CLMF p35); IL-12 subunit p35; NK cell stimulatory factor chain 1(NKSF1); NKSF1; interleukin 12A; P35; CLMF; NFSK; NKSF1;
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human IL-12
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Tumor immunology > Cytokines > Interleukins

    Immunology > Innate Immunity > Cytokines > Interleukins

    亚基Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
    亚细胞定位Secreted.
    相似性Belongs to the IL-6 superfamily.
    功能Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料bs-0767P is one synthetic peptide derived from mouse IL-12. IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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