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ITGA11 Rabbit pAb, FITC conjug

ated(bs-13771R-FITC)-100ul
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  • ¥2980
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  • bs-13771R-FITC
  • 2025年10月15日
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      100ul

    产品编号bs-13771R-FITC
    英文名称ITGA11 Rabbit pAb, FITC conjugated
    中文名称FITC标记的整合素α11抗体
    英文别名integrin a11; Integrin alpha 11; Integrin alpha-11; ITA11_HUMAN; Integrin α11.
    产品应用IF=1:100-500, ICC/IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ITGA11
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Invasion/microenvironment > ECM > Cell adhesion > Integrins

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Integrins > Alpha

    亚细胞定位Membrane.
    组织特异性According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver.
    相似性Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
    功能Integrin alpha-11/beta-1 is a receptor for collagen.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits, which heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen (COL) and Vitronectin. Certain Integrins can also bind to soluble ligands, such as Fibrinogen, or to counterreceptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), leading to cellular aggregation. Integrin ?1, also known as ITGA11 or MSTP018, is a 1,189 amino acid single-pass type I membrane protein that contains one VWFA domain and seven FG-GAP repeats. Expressed at high levels in heart and uterus and present at lower levels in pancreas, kidney, skeletal muscle, placenta, lung, colon and brain, Integrin alpha 11 exists as a heterodimer with Integrin beta1 and functions as a receptor for collagen.

     

    应用推荐稀释比例
    {IF}{1:100-500}
    {ICC/IF}{1:100-500}

     

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    图标文献和实验
    相关实验
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    • Fluorochrome Absorption and Emission

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