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100ul
| 产品编号 | bs-5803R-IRDye800CW |
| 英文名称 | API2/BIRC3 Rabbit pAb, IRDye 800CW conjugated |
| 中文名称 | IRDye 800CW标记的凋亡抑制因子2抗体 |
| 英文别名 | cIAP2; CIAP 2; CIAP-2; Inhibitor of apoptosis protein 1; AIP 1; AIP1; API 2; API2; Apoptosis inhibitor 2; Baculoviral IAP repeat containing 3; Baculoviral IAP repeat containing protein 3; Baculoviral IAP repeat-containing protein 3; BIRC 3; BIRC3; BIRC3_HUMAN; C IAP2; C-IAP2; CIAP 2; CIAP2; HAIP 1; HAIP1; HIAP 1; HIAP-1; HIAP1; IAP homolog C; IAP-1; Inhibitor of apoptosis protein 1; MALT 2; MALT2; Mammalian IAP homolog C; MIHC; RING finger protein 49; RNF49; TNFR2 TRAF signaling complex protein 1; TNFR2 TRAF signalling complex protein; TNFR2-TRAF-signaling complex protein 1. |
| 产品应用 | WB=1000-10000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human cIAP2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell Death > Apoptosis > Apoptosis Markers > Caspases Cancer > Cell Death > Apoptosis > Metabolism Cancer > Cell Death > Apoptosis > Receptors > Death receptors & ligands > IAPs Cancer > Cell Death > Necroptosis Cancer > Invasion/microenvironment > Apoptosis > Caspases Cancer > Invasion/microenvironment > Apoptosis > Death receptors & ligands > IAPs Cell Biology > Apoptosis > Intracellular > Survivin / IAPs Metabolism > Pathways and Processes > Metabolism processes > Apoptosis |
| 亚基 | Interacts with DIABLO/SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). Interacts with RIP1, RIP2, RIP3, RIP4 and USP19. |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 组织特异性 | Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes. |
| 相似性 | Belongs to the IAP family. Contains 3 BIR repeats. Contains 1 CARD domain. Contains 1 RING-type zinc finger. |
| 功能 | Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). |
| 应用 | 推荐稀释比例 |
| {WB} | {1000-10000} |
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API2/BIRC3 Rabbit pAb, IRDye 800CW conjugated(bs-5803R-IRDye800CW)-100ul
¥2980





