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| 产品编号 | bsR-0346P |
| 英文名称 | Rat IgM / RBITC |
| 中文名称 | 罗丹明标记大鼠IgM（同型对照) |
| 英文别名 | Rat Immunoglobulin M/RBITC Isotype Control |
| 中文别名 | 荧光素罗丹明标记大鼠IgM |
| 性状 | Liquid |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存条件 | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |
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文献和实验volume to bring the cells to the following concentrations: Type Cell Concentration mouse or rat 1.5 x 106 cells per ml hamster 0.5 - 1.0 x 106 cells per ml
ml using I-20. Centrifuge at 4°C and resuspend in HAT medium at the appropriate volume to bring the cells to the following concentrations: Type Cell Concentration mouse or rat 1.5 x
可能与其他物种发生交叉反应， 除非特异性的经过交叉反应物种的吸附处理。在抗体描述中，经过其他物种的吸附处理的抗体标有“ (min X …Sr Prot) ”字样 。 Anti-IgG (H+L) 这类抗体和 IgG 分子的重链和轻链都可以反应，比如，和 IgG 分子的 Fc ， F(ab ’)2/Fab 部分。 Anti-IgG (H+L) 抗体也可以和其他的免疫球蛋白家族（ IgM ， IgA ，IgD,IgE ）和亚家族反应，因为所有的免疫球蛋白都有相同的轻链（或者 κ 链
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