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bs-48075P

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  • 2025年10月15日
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      10ug/50ug/500ug

    规格:10ug产品价格:¥750.0
    规格:50ug产品价格:¥2250.0
    规格:500ug产品价格:¥9000.0
    产品编号bs-48075P
    英文名称Recombinant human LIF protein (Active, CHO)
    中文名称重组人白血病抑制因子
    英文别名Leukemia Inhibitory Factor; Differentiation-Stimulating Factor; D Factor; Melanoma-Derived LPL Inhibitor; MLPLI; Emfilermin; HILDA;
    性状Lyophilized
    纯化方法AC
    理论分子量19.7
    储存液Lyophilized from 0.22μm-filtered solution in PBS, 5% mannital, 0.01% Tween 80, pH7.4
    研究领域

    Cancer > Cell cycle > Cell differentiation

    Cell Biology > Cell Cycle > Cell differentiation

    Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Tumor Suppressors

    Immunology > Innate Immunity > Cytokines

    Immunology > Innate Immunity > Cytokines > IL6 Related

    Neuroscience > Neurology process > Neurogenesis

    亚细胞定位Secreted.
    相似性Belongs to the LIF/OSM family.
    功能LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
    保存条件Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 8℃ under sterile conditions after reconstitution.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The leukemia inhibitory factor- LIF is a kind of cell factor that has various living creature functions.It has the leukemia cell of inducement to divide, regulating the growth metabolism of the bone organization, maintaining the basic characteristic of the Embryonicstem celles and promoting the mankind build the blood stem cell to divide to propagate, promote the cholinergic neuron to divide, obstruct the fat cell to synthesize, stimulate the muscle cell growth, regulate the liver cell to expect to respond the egg white to synthesize etc. in the acute the biology activity etc. function.

     

     

    产品细节图片1
    Measured in a cell proliferation assay using TF-1 cells.

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    图标文献和实验
    相关实验
    • CHO细胞株的部分特性

      deposit: NoPrice_code: AAvailability in cell line catalogues: ATCC CCL 61; IZSBS BS CL15; DSMZ ACC 110;Bibliographic references:J Exp Med 1958;108:945 Proc Nat Acad Sci USA 1968;60:1275CHO-K1 (hamster, Chinese, ovary)Morphology: epithelial-likeSpecies

    • (交流)原位杂交操作技术步骤

      后置-20℃保存 20×SSC 10×PBS (DEPC处理的)含50%甲酰胺的杂交液(HS)--- 1ml分装后置-20℃保存 10×阻断液(10×BS) Buffer I Buffer II Buffer III 探针(P) 抗Dig-Ap NBT/BCIP 二、操作流程: 1)  脱蜡至水: 二甲苯5min×2 → 90%乙醇5min → DEPC水洗涤5min×2 2)  杂交前处理: 1×PBS洗涤5min → 蛋白酶K(终浓度20ug/ml in PBS)37℃

    • 申请上传wiley的PROTEOMICS 新书(已上传)

      in Renal Cancer (p 73-96) Rosamonde E. Banks, Peter J. Selby Chapter 6: Heat Shock Protein 27 in Cancer (p 97-109) Dr. Cecilia Sarto, Dr. Fulvio Magni, BS. Cristina Valsecchi, Prof. Dr. Paolo Mocarelli Chapter 7: Proteomic Approaches for Biomarker

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