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- bs-48094P
- 2026年10月10日
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- 技术资料
- 规格：
100mg
| 产品编号 | bs-48094P |
| 英文名称 | Recombinant human Fetuin A protein (Active, CHO) |
| 中文名称 | 重组人胎球蛋白A |
| 英文别名 | Alpha-2-HS-Glycoprotein; Alpha-2-Z-Globulin; Ba-Alpha-2-Glycoprotein; Fetuin-A; AHSG; FETUA; |
| 性状 | Lyophilized |
| 纯化方法 | AC |
| 理论分子量 | 32.9 |
| 储存液 | Lyophilized from a 0.22μm-filtered solution containing 10mM PB, pH7.4 |
| 研究领域 | Cardiovascular > Blood > Serum Proteins Metabolism > Types of disease > Obesity Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. |
| 相似性 | Belongs to the fetuin family. Contains 2 cystatin fetuin-A-type domains. |
| 功能 | Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 8℃ under sterile conditions after reconstitution. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq, Jul 2008] |
Measured in a cell proliferation assay using B16-F1 cells. Human Fetuin A stimulates adhesion of B16-F1 cells. The ED50 for this effect is 50-200 μg/mL.
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rHu AHSG | Fetuin A Protein, Tag free (Active, CHO)(bs-48094P)-100mg
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