- ￥880
- Bioss
- bs-13453P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-13453P |
| 英文名称 | GMDS Antibody Blocking Peptide |
| 中文名称 | 甘露糖脱水酶GMDS封闭多肽 |
| 英文别名 | GDP D mannose dehydratase; GDP mannose 4 6 dehydratase; GDP-D-mannose dehydratase; GDP-mannose 4,6 dehydratase; GMD; Gmds; GMDS_HUMAN; OTTHUMP00000017756; OTTHUMP00000232770; SDR3E1; Short chain dehydrogenase/reductase family 3E member 1. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Signal Transduction > Metabolism > Energy Metabolism |
| 相似性 | Belongs to the GDP-mannose 4,6-dehydratase family. |
| 功能 | Conversion of GDP-D-mannose to GDP-4-keto-6-D-deoxymannose. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GMD is a 372 amino acid protein that utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. GMD mutations are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. The gene encoding GMD maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. |
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GMDS | GMD Ab Blocking Peptide(bs-13453P)-500ug
￥880
