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- Bioss
- bs-14604P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14604P |
| 英文名称 | ENTPD8 Antibody Blocking Peptide |
| 中文名称 | ENTPD8蛋白封闭多肽 |
| 英文别名 | E NTPDase 8; ENTP8_HUMAN; EC 3.6.1.5; ecto-ATP-diphosphohydrolase; Ectonucleoside triphosphate diphosphohydrolase 8; GLSR2492; iver ecto ATP diphosphohydrolase; NTPDase 8; nucleoside triphosphate diphosphohydrolase-8; UNQ2492. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 翻译后修饰 | N-glycosylated. |
| 相似性 | Belongs to the GDA1/CD39 NTPase family. |
| 功能 | ENTPD8 is a canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP. There are two different isoforms. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Members of the ecto-nucleoside triphosphate diphosphohydrolase (eNTPDase) protein family are glycosylated enzymes that hydrolyze nucleoside 5’-triphosphates and 5’-diphosphates in extracellcular space. The enzymatic activities of eNTPDase are dependent on cations such as magnesium and calcium. Members of this protein family differ in their affinities for triphosphates versus diphosphates as substrate material. NTPDase8, also known as ENTPD8 (ectonucleoside triphosphate diphosphohydrolase 8) or E-NTPDase 8, is a 495 amino acid multi-pass membrane protein belonging to the GDA1/CD39 NTPase family. As a canalicular ectonucleoside NTPDase, NTPDase8 is involved in hepatic NTPDase activity and helps concentrate extracellular nucleotides. NTPDase8 binds calcium as a cofactor, becomes glycosylated following translation and exists as two alternatively spliced isoforms. |
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ENTPD8 Antibody Blocking Peptide(bs-14604P)-500ug
￥880
