- ￥580 - 5680
- Bioss
- bs-0884P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
100ug/20ug/500ug
| 规格： | 100ug | 产品价格： | ￥1880.0 |
|---|---|---|---|
| 规格： | 20ug | 产品价格： | ￥580.0 |
| 规格： | 500ug | 产品价格： | ￥5680.0 |
| 产品编号 | bs-0884P |
| 英文名称 | Recombinant human IL-1Ra protein, His |
| 中文名称 | 重组人白介素-1受体拮抗剂蛋白 |
| 英文别名 | Recombinant Human Interleukin-1 receptor antagonist His Tag; Recombinant human IL-1Ra protein, His |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 17 |
| 实际分子量 | 20 kDa |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | PBS (pH7.4). |
| 亚细胞定位 | Isoform 1: Secreted. Isoform 2, 3, 4: Cytoplasm. |
| 组织特异性 | The intracellular form of IL1RN is predominantly expressed in epithelial cells. |
| 功能 | Inhibits the activity of interleukin-1 by binding to eceptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | IL-1RA is a member of the interleukin 1 cytokine family. IL1Ra is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL1β. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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Recombinant human IL-1Ra protein, His(bs-0884P)-100ug/20ug/500ug
￥580 - 5680
