- ￥800
- Bioss
- bs-2621P
- 2025年10月16日
企业认证
相关产品推荐更多 >
![[Glu1]-Fibrinopeptide B peptide(Y-0493)-0.5mg/1mg](https://img1.dxycdn.com/p/s14/2025/1016/917/2599056929396368791.jpg!wh200)
![EBNA-3B [Human herpesvirus 4] Antibody Blocking Peptide(bs-4698P)-500ug](https://img1.dxycdn.com/p/s14/2025/1016/051/8444607312190468791.jpg!wh200)
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2621P |
| 英文名称 | IL21 Antibody Blocking Peptide |
| 中文名称 | 白介素21封闭多肽 |
| 英文别名 | IL 21;IL-21; Interleukin 21; Interleukin21; Za11; IL21_HUMAN; Interleukin-21; interleukin-21 isoform; OTTHUMP00000164088. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. |
| 相似性 | Belongs to the IL-15/IL-21 family. |
| 功能 | Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | IL-21 is a typical family I cytokine with broad pleiotropic actions and is primarily produced by T follicular helper cells, Th17, and natural killer T cells in response to antigenic stimulation. Il-21 generally enhances antigen-specific responses of immune cells. It controls the activation, proliferation, differentiation, cytotoxicity, and survival of various target immune cells. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 elicits its effect through binding to IL-21R, which also contains the gamma chain found in other cytokine receptors such as IL-2, IL-4, IL-7, IL-9 and IL-15. IL-21/IL-21R interaction triggers a cascade of events, which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant Human IL-21 is a 15.4 kDa protein consisting of 132 amino acid residues. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
IL21 Antibody Blocking Peptide(bs-2621P)-500ug
￥800
