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500ug
| 产品编号 | bs-14597P |
| 英文名称 | ENOX1 Antibody Blocking Peptide |
| 中文名称 | ENOX1蛋白封闭多肽 |
| 英文别名 | bA64J21.1; Candidate growth related and time keeping constitutive hydroquinone [NADH] oxidase; Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase; cCNOX; Cell proliferation inducing gene 38 protein; Cell proliferation-inducing gene 38 protein; cNOX; Constitutive Ecto NOX; Constitutive Ecto-NOX; Ecto NOX disulfide thiol exchanger 1; ENOX1; ENOX1_HUMAN; FLJ10094; OTTHUMP00000018332; PIG38; Proliferation inducing protein 38; Protein disulfide-thiol oxidoreductase. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane. Secreted; extracellular space. Extracellular and plasma membrane-associated. |
| 组织特异性 | Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells. |
| 相似性 | Belongs to the ENOX family. _x000D_ Contains 1 RRM (RNA recognition motif) domain. |
| 功能 | Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
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文献和实验Dual-Color ELISPOT Assay for the Simultaneous Detection of IL-2 and/or IFN- Secreting T Cells
, activate AEC buffer using H2 O2 (see Step 25). Anti-CD3 monoclonal antibody (mAb) (Fisher Scientific) Blocking buffer for ELISPOT assay CEF peptide pool (available from the NIH AIDS Research and Reagent Program and other commercial
0.3% hydrogen peroxide (prepare immediately before use) Blocking buffer (see recipe ) HCV‐specific primary antibody (Ab), e.g
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