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CSF2RA Antibody Blocking Pepti

de(bs-1457P)-500ug
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  • 2025年10月16日
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      500ug

    产品编号bs-1457P
    英文名称CSF2RA Antibody Blocking Peptide
    中文名称粒细胞-巨噬细胞集落刺激因子受体α封闭多肽
    英文别名GM-CSF Receptor alpha; CD116; CD116 antigen; Colony Stimulating Factor 2 Receptor Alpha; Colony stimulating factor 2 receptor alpha chain; CSF 2R; CSF2RA; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM CSF R alpha; GM CSF receptor alpha subunit; GMCSFR; GMR; Granulocyte Macrophage Colony Stimulating Factor Receptor Alpha Chain; GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CDw116; CSF2R_MOUSE; Granulocyte-macrophage colony-stimulating factor receptor subunit alpha.
    纯化方法HPLC
    研究领域

    Immunology > Innate Immunity > Cytokines > CSFs

    Immunology > Innate Immunity > Macrophage / Inflamm.

    Stem Cells > Mesenchymal Stem Cells > Negative Markers

    亚基Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.
    亚细胞定位Cell membrane; Single-pass type I membrane protein. Isoform 3: Secreted (Probable). Isoform 4: Secreted (Probable). Isoform 6: Secreted (Probable).
    相似性Belongs to the type I cytokine receptor family. Type 5 subfamily.
    功能Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq].

     

     

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