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EML1 Antibody Blocking Peptide

(bs-14586P)-500ug
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  • bs-14586P
  • 2025年10月16日
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      500ug

    产品编号bs-14586P
    英文名称EML1 Antibody Blocking Peptide
    中文名称EML1蛋白封闭多肽
    英文别名echinoderm microtubule associated protein like 1; Echinoderm microtubule-associated protein-like 1; ELP79; EMAL1_HUMAN; EMAP; EMAP-1; EMAPL; Eml1; FLJ45033; HuEMAP; HuEMAP-1.
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microtubules > MT Associated Proteins > MAP

    亚细胞定位Cytoplasm; cytoskeleton.
    组织特异性Ubiquitous; expressed in most tissues with the exception of thymus and peripheral blood lymphocytes.
    相似性Belongs to the WD repeat EMAP family.
    Contains 10 WD repeats.
    功能May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

     

     

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