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- Bioss
- bs-22317P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-22317P |
| 英文名称 | SLC16A7/MCT2 Antibody Blocking Peptide |
| 中文名称 | 单羧酸转运蛋白2封闭多肽 |
| 英文别名 | MCT 2; MCT; Monocarboxylate transporter 2; MonocarboxylateTransporter 2; MOT2; MOT2_HUMAN; SLC16A7; Solute carrier family 16 member 7; Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of carbohydrates Metabolism > Pathways and Processes > Metabolic signaling pathways > Carbohydrate metabolism Signal Transduction > Metabolism > Plasma Membrane > Channels |
| 亚基 | Interacts with GRID2IP. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells. |
| 相似性 | Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. |
| 功能 | Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters (MCTs) mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate (summary by Lin et al., 1998 [PubMed 9786900]).[supplied by OMIM, Feb 2011]. |
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SLC16A7 | MCT2 Ab Blocking Peptide(bs-22317P)-500ug
￥880
